A NEW STUDY THAT PROVES A SUCCESSFUL TREATMENT FOR COLORECTAL CANCER BY USING HIGH DOSES OF VITAMIN C….

About half of the cases of colorectal cancer contain genetic mutations which lead to resistance to the therapy. Previous studies had found that colorectal cancer cells which contain these mutations have overactive metabolism of sugar. But, the new study conducted by a team of scientists has found that these mutated colorectal cancer cells could be selectively killed by intake a high doses of vitamin C.

HIGH-DOSE VITAMIN C KILLS COLORECTAL CANCER CELLS

The study showed that vitamin C is transported in the colorectal cancer cells by using the same route as the glucose, a sugar type that is used for the energy production in the cells. It was determined that the intake of vitamin C in the mutant cancer cells is significantly higher than in the non-mutant cells. The research showed that the treatment with high doses of vitamin C, results in selective killing of the mutant cancer cells. The intake of high doses of vitamin C creates an imbalance in the sugar and energy metabolism, that seriously reduces the survival and growth of the mutant cancer cells unlike the non-mutant cancer cells which absorption of vitamin C is less. In experiments conducted on mice, application of high doses of vitamin C for 3-4 weeks effectively reduces the size of the intestinal tumor that contains genetic mutations in comparison with untreated animals.

According the study, high doses of vitamin C is possible to be administered in humans intravenously, without any toxicity. The efficacy of vitamin C in the treatment of colorectal cancer should be tested further in clinical trials.

 

 

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